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Disrupting & Redefining
Genetic Diagnostics
& Drug Discovery

functional and clinical impact
of all gene mutations

Pharma/Biotech

Clinical Diagnostics
Connecting Mutations
to Health

proprietary cell-outcome
genetic variant libraries

Pharma/Biotech

Clinical Diagnostics
Enabling Precision
Medicine
100% precision care with
guess-free advanced genetics

Genetic Testing

Speak With Us
Discovering Whole
Gene Biomarkers

accurate diagnostics with
precision whole gene
biomarker panels

See How We Help

Book a Consultant
Improving Genetic
Diagnostics

Analyze functional variation
in gene coding and
promoter regions

See How We Help

Book a Consultant
Rescuing Failed
Clinical Trials
convert failed conventional
drugs to approved precision drugs

Learn More

Get Help
Identifying Off-Target
Drug Interactions
minimize side effects and
identify new indications

Learn More

Reach Out
Increasing Clinical
Trial Success

super-precision genetic-based
design increasing safety and efficacy

Next Steps

Arrange to Speak
Developing
New Drugs

eliminate adverse events
and non-responders before
an expensive clinical trial

Develop Strategy

Speak With Expert
Resistance Mapping for
Companion Diagnostics

powering precision prescriptions
with whole gene drug
resistance profiling

Find Answers

Reach Out

Heligenics believes that people can live healthier lives. We recognize major healthcare problems can be solved through advanced analysis of the function of genetic variation.

Do you want to modernize and improve healthcare with us?

Heligenics believes that people can live healthier lives. We recognize major healthcare problems can be solved through advanced analysis of the function of genetic variation.

Do you want to modernize and improve healthcare with us?

Problem

The function of most amino acid substitutions is largely unknown. The functional and clinical effect of almost all genetics changes remains unknown.

Disruption

The GigaAssay technology advances the science of drug development and rescue along with genetic diagnostics using a proprietary methodology, shortening research from years to months.

Solution

Heligenics solves this problem by experimentally measuring the impact of huge numbers of genetic changes at one time.

What We Have Been Saying. . .

HeligenicsFollow536737

https://t.co/ejWKEPIVW0 🧬🧪👨‍🔬 Connecting #Mutations to #Health. Using Heligenics cell-based #genetic variant libraries.

Heligenics @heligenics·

15 Mar 1503734334016004100

Check out Heligenics on the PharmasAlmanac website
https://www.pharmasalmanac.com/r250-trip/day-24

Reply on Twitter 1503734334016004100 Retweet on Twitter 1503734334016004100 Like on Twitter 1503734334016004100

Heligenics @heligenics·

15 Mar 1503733964699185153

A big thanks to Nigel for exploring Heligenics!
https://www.linkedin.com/posts/walkernigel_pharmaceuticals-pharmaceuticalindustry-pharmasalmanac-activity-6909495832421535745-uud2/

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Heligenics @heligenics·

8 Mar 1501286291983384584

This is a great video about the story of Heligenics. Please pass it on.

https://vimeo.com/thatsnice/review/685883105/9fdcc5d0ec

Reply on Twitter 1501286291983384584 Retweet on Twitter 1501286291983384584 Like on Twitter 1501286291983384584

Heligenics @heligenics·

22 Jan 1484972088175706112

Heligenics is looking for an experienced Flow Cytometry contultant. Apply at https://forms.gle/bQnaLcUNoPkf7Vy67

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Heligenics @heligenics·

22 Nov 1462880401857277955

Heligenics meets the Pharmas Almanac tour of 50 states. See day 24 in Las Vegas - https://www.pharmasalmanac.com/r250-trip/day-24

Reply on Twitter 1462880401857277955 Retweet on Twitter 1462880401857277955 Like on Twitter 14628804018572779551

Heligenics @heligenics·

10 Nov 1458483856529510401

Consider double mutant HML libraries to examine epistasis with Heligenics. We are seeing very interesting results.

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Heligenics @heligenics·

24 Oct 1452301855002963985

Our experiments at Heligenics show that it is way better to look at single molecules than single cells.

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Heligenics @heligenics·

24 Oct 1452301448637726727

Nigel Walker's Biotech tour of 50 states included a fun visit to Heligenics. Nigel was so much fun! https://www.linkedin.com/feed/update/urn%3Ali%3AugcPost%3A6853990795159097344/?actorCompanyId=43239231

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Heligenics @heligenics·

24 Oct 1452073735033217026

Over the past decade the world is moving from bulk tissue analysis to single-cell analysis. Heligenics is moving us from single cells to single molecules!

Reply on Twitter 1452073735033217026 Retweet on Twitter 14520737350332170261 Like on Twitter 14520737350332170262

Heligenics @heligenics·

24 Oct 1452073385261998082

Heligenics is at the BioEurope conference this week and talking to many potential partners.

Reply on Twitter 1452073385261998082 Retweet on Twitter 1452073385261998082 Like on Twitter 14520733852619980822

Heligenics @heligenics·

8 Sep 1435719904187928580

(1/3)
We see no reason why the GigaAssay cannot be applied to other genes and assays to address other important questions in biomedical sciences. We identify a pattern in Tat where PPIs and PTMs are selected for robustness, while key structural elements or ...

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Heligenics @heligenics·

7 Sep 1435313320899203074

(1/2)
"Fig. 2 and Supplementary Fig. S18E https://www.researchsquare.com/article/rs-708936/v1 reveals previously unrecognized limitations of truncation mutant studies. The context also produces a framework to identify ambiguities and potential misinterpretation of mutant data regarding ...

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Heligenics @heligenics·

3 Sep 1433864602220064772

We have mapped out 95% of Variants and their functional effect on the cell for ERBB2.
You have a drug Trastuzumab that binds to ERBB2.
If we put the two together in our experiment we could help you. [email protected]

#ERBB2 #Drugtrial

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Heligenics @heligenics·

31 Aug 1432762092658982913

(1/3)
1,300 square feet at [email protected]’ satellite location at 833 Las Vegas Blvd. North (former Library) is where Heligenics now stand. The [email protected] at 300 S. 4th Street, which opened in September 2019, is fully occupied with ten tenants, prompting the city to expand its ...

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Heligenics @heligenics·

27 Aug 1431368051283218434

Modernize your clinical trials today at http://Heligenics.com and download our Superprecsion Clinical Trial Success PDF file, exclusively made for you.

#PrecisionClinicalTrial #ModernizeDrugs

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Heligenics

139 subscribers

Through a massively parallel in-vivo process called the GigaAssay, Heligenics produces what is called a Gene Mutation/Function Library (“GMLs”). Each GML measures the impact of all possible amino acids substitutions in the functional target protein. Heligenics answers challenges across three main markets: Genetic testing, development of new drugs, and rescue of drugs that have failed clinical trials.

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Solutions to help . . .

Pharma/Biotech

Clinical Diagnostics

It can take years to identify a single genetic marker

Heligenics measures the impact of all gene mutations in months

Join the functional genome revolution!
Reach out today for more information.

Contact Us

Disrupting & Redefining
Genetic Diagnostics
& Drug Discovery

functional and clinical impact
of all gene mutations

Connecting Mutations
to Health

proprietary cell-outcome
genetic variant libraries

Enabling Precision
Medicine

100% precision care with
guess-free advanced genetics

Discovering Whole
Gene Biomarkers

accurate diagnostics with
precision whole gene
biomarker panels

Improving Genetic
Diagnostics

Analyze functional variation
in gene coding and
promoter regions

Rescuing Failed
Clinical Trials

convert failed conventional
drugs to approved precision drugs

Identifying Off-Target
Drug Interactions

minimize side effects and
identify new indications

Increasing Clinical
Trial Success

super-precision genetic-based
design increasing safety and efficacy

Developing
New Drugs

eliminate adverse events
and non-responders before
an expensive clinical trial

Resistance Mapping for
Companion Diagnostics

powering precision prescriptions
with whole gene drug
resistance profiling

Heligenics believes that people can live healthier lives. We recognize major healthcare problems can be solved through advanced analysis of the function of genetic variation.

Do you want to modernize and improve healthcare with us?

Heligenics believes that people can live healthier lives. We recognize major healthcare problems can be solved through advanced analysis of the function of genetic variation.

Do you want to modernize and improve healthcare with us?

Problem

Disruption